An Introduction to Dosing for Cisplatin
The dose of cisplatin
that your healthcare provider recommends will vary, depending on a number of factors, including:
- Your height and weight
- The type of cancer being treated
- How you respond to cisplatin (especially whether you develop dangerous side effects)
- Other medications you may be taking (your particular chemotherapy regimen)
- Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically instructs you to do so.
Recommended Cisplatin Dosage
Your healthcare provider will base your cisplatin dosage on your body surface area (which is calculated using your height and weight). Your dosage amount will also depend on your particular chemotherapy regimen, as well as the particular type of cancer being treated. Also, your dosage may need to be reduced (or given less frequently) if you develop dangerous or intolerable cisplatin side effects
General Information on Taking Cisplatin
Some considerations for people taking cisplatin include the following:
- Cisplatin comes in injectable form. Your healthcare provider will administer it intravenously via an infusion (also known as an "IV drip"), typically every three or four weeks for a certain number of treatments. The total length of time the infusion will last will depend on several factors but can be quite long (often a six- to eight-hour period, sometimes longer).
- Let your healthcare provider know immediately if you feel any burning or stinging while receiving the infusion, as this may be a sign that the medication is leaking outside the vein (a situation which can be quite serious).
- It is important that you are well hydrated before each round of this medication. In fact, your healthcare provider will probably recommend that you receive IV fluids ("pretreatment hydration") before each dose. This may help to prevent kidney toxicity. The pretreatment hydration IV is typically given over several hours (8 to 12 hours, sometimes longer).
- Most people receive this medication at their healthcare provider's office, a hospital, or at an "infusion center."
- For the medication to work properly, it must be taken as prescribed. Chemotherapy works best when it is taken "on schedule," although often the side effects that occur limit a person's ability to stay on schedule with the full dose.
- If you are unsure about anything related to your dosage or cisplatin dosing in general, please talk with your healthcare provider, nurse, or pharmacist.