Ovarian Cancer Treatment by Stage

Stage I and II Ovarian Epithelial Cancer
Treatment of stage I and stage II ovarian cancer may include:
  • Total abdominal hysterectomy, bilateral salpingo-oophorectomy, and omentectomy
  • Total abdominal hysterectomy, unilateral salpingo-oophorectomy, and omentectomy.
In both procedures, the lymph nodes and other tissues in the pelvis and abdomen are removed and examined under the microscope to look for cancer cells.
Stage III and IV Ovarian Epithelial Cancer
Treatment of stage III and stage IV ovarian epithelial cancer may include:
  • Surgery to remove the tumor
  • Total abdominal hysterectomy
  • Bilateral salpingo-oophorectomy
  • Omentectomy.
After surgery, treatment may include combination chemotherapy or combination chemotherapy followed by second-look surgery (surgery performed after the initial surgery to determine whether any tumor cells remain).
Recurrent Ovarian Epithelial Cancer
For recurrent ovarian epithelial cancer, treatment may include chemotherapy with or without surgery.

Ovarian Cancer Treatment by Stage for Ovarian Germ Cell Cancer

Ovarian germ cell cancer is broken down into the following stages, each one with its specific treatment options:


  • Stage I
  • Stage II
  • Stage III
  • Stage IV
  • Recurrent.


Stage I Ovarian Germ Cell Cancer
For stage I ovarian germ cell cancer, treatment will depend on whether the tumor is dysgerminoma or another type of germ cell tumor.
Treatment of dysgerminoma may include:
  • Unilateral salpingo-oophorectomy, with or without lymphangiography (an x-ray study of the lymph system -- the tissues and organs that filter and destroy harmful substances and help fight infection and disease)
  • Unilateral salpingo-oophorectomy, with or without or computed tomography scan (a series of detailed pictures of areas inside the body created by a computer linked to an x-ray machine)
  • Unilateral salpingo-oophorectomy followed by observation (closely monitoring a patient's condition without giving any treatment until symptoms appear or change)
  • Unilateral salpingo-oophorectomy followed by radiation therapy
  • Unilateral salpingo-oophorectomy followed by chemotherapy.
Treatment of other germ cell tumors may include unilateral salpingo-oophorectomy followed by careful observation or unilateral salpingo-oophorectomy, sometimes followed by combination chemotherapy.
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Ovarian Cancer Treatments

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