Thiotepa Side Effects

Some of the possible side effects of thiotepa can include fatigue, loss of appetite, and hair loss. Although most people who use this drug will develop some type of reaction, there are no specific statistics available on which problems occur the most. There are also potentially dangerous problems, such as fever, blurred vision, and persistent vomiting, that require immediate medical treatment.


An Introduction to Side Effects of Thiotepa

As with any chemotherapy medicine, thiotepa (Thioplex®) can cause side effects. In fact, most people will experience some type of reaction to this drug, and some problems can be quite significant. Talk to your healthcare provider about ways to prevent or lessen reactions to this medicine.
(This article covers many, but not all, of the possible side effects with thiotepa. Your healthcare provider can discuss a more complete list with you.)

Serious Thiotepa Side Effects

Some side effects of thiotepa include but are not limited to:
  • Signs of an allergic reaction (which can occur during or soon after receiving your dose), such as:
    • Rash
    • Hives
    • Itching
    • Swelling of the mouth, tongue, face, lips, or throat
    • Wheezing
    • Difficulty breathing or swallowing
  • Signs of anemia, such as:
    • Unusual tiredness
    • Weakness
    • Pale skin
    • Shortness of breath
  • Unusual bruising or bleeding
  • Black, tarry, or bloody stools
  • Blood in the urine
  • Nosebleeds
  • Swelling, burning, stinging, pain, or leakage of fluid around your injection site
  • Painful or difficult urination
  • Redness, itching, or irritation of one or both eyes
  • Blurred vision
  • Persistent or extreme nausea and vomiting.
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Thiotepa Drug Information

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