Topotecan is approved for the treatment of lung, ovarian, and cervical cancer. This prescription chemotherapy medication works by interfering with the normal formation of DNA. The drug comes in capsule and injectable form, and is typically used once daily for three to five days, every 21 days. Possible side effects include nausea, vomiting, and anemia.

What Is Topotecan?

Topotecan (Hycamtin®) is a prescription chemotherapy medication. The oral version of this medication is approved to treat lung cancer, and the intravenous (IV) form is approved to treat lung cancer, ovarian cancer, and cervical cancer.
(Click What Is Topotecan Used For? for more information on what the medication is used for, including possible off-label uses.)

Are There Side Effects?

As with any medicine, topotecan may cause side effects. Like most forms of chemotherapy, topotecan is capable of causing serious side effects.
Some of the possible side effects include but are not limited to:
  • Anemia
  • Low white blood cells
  • Low blood platelets
  • Nausea
  • Vomiting
  • Diarrhea.
(Click Side Effects of Topotecan to learn more, including potentially serious side effects that you should report immediately to your healthcare provider.)

Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to taking topotecan if you have:
  • Any infection
  • Kidney disease, such as kidney failure (renal failure)
  • Any bleeding
  • A history of interstitial lung disease (ILD)
  • Pulmonary fibrosis
  • Any allergies, including allergies to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and nonprescription medications, vitamins, and herbal supplements.
(Click Precautions and Warnings With Topotecan to learn more, including information on who should not take the drug.)

Topotecan Chemotherapy Information

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